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Ischemic neuroprotectant PKCε restores mitochondrial glutamate oxaloacetate transaminase in the neuronal NADH shuttle after ischemic injury

The preservation of mitochondrial function is a major protective strategy for cerebral ischemic injuries. Previously our laboratory demonstrated that protein kinase C epsilon (PKCε) promotes the synthesis of mitochondrial Nicotinamide adenine dinucleotide (NAD(+)). NAD(+) along with its reducing equ...

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Publicat a:Transl Stroke Res
Autors principals: Xu, Jing, Khoury, Nathalie, Jackson, Charles W., Escobar, Iris, Stegelmann, Samuel D., Dave, Kunjan R., Perez-Pinzon, Miguel A.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048657/
https://ncbi.nlm.nih.gov/pubmed/31473978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-019-00729-4
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