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Membrane stabilizer Poloxamer 188 improves yield of primary isolated rat cardiomyocytes without impairing function

Intact cardiomyocytes are used to investigate cardiac contractility and evaluate the efficacy of new therapeutic compounds. Primary enzymatic isolation of adult rodent cardiomyocytes has limitations, including low cardiomyocyte survival, which is likely due to ischemic conditions and/or membrane dam...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Physiol Rep
Prif Awduron: Czeiszperger, Teresa L., Wang, Madison P., Chung, Charles S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048379/
https://ncbi.nlm.nih.gov/pubmed/32109347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14382
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