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Membrane stabilizer Poloxamer 188 improves yield of primary isolated rat cardiomyocytes without impairing function

Intact cardiomyocytes are used to investigate cardiac contractility and evaluate the efficacy of new therapeutic compounds. Primary enzymatic isolation of adult rodent cardiomyocytes has limitations, including low cardiomyocyte survival, which is likely due to ischemic conditions and/or membrane dam...

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Bibliografiske detaljer
Udgivet i:Physiol Rep
Main Authors: Czeiszperger, Teresa L., Wang, Madison P., Chung, Charles S.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048379/
https://ncbi.nlm.nih.gov/pubmed/32109347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14382
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