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Neonatal immune challenge followed by adult immune challenge induces epigenetic-susceptibility to aggravated visceral hypersensitivity

BACKGROUND: Abdominal pain is one of the major symptoms of inflammatory Bowel Disease (IBD). The inflammatory mediators released by colon inflammation are known to sensitize the afferent neurons, which is one of the contributors to abdominal pain. However, not all IBD patients have abdominal pain, a...

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Detalhes bibliográficos
Publicado no:Neurogastroenterol Motil
Main Authors: Aguirre, Jose E, Winston, John H., Sarna, Sushil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048321/
https://ncbi.nlm.nih.gov/pubmed/28439935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nmo.13081
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