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Adrenergic Stimulation Mediates Visceral Hypersensitivity to Colorectal Distension following Heterotypic Chronic Stress

BACKGROUND & AIMS: Chronic stress exacerbates or causes relapse of symptoms such as abdominal pain and cramping in patients with irritable bowel syndrome (IBS). We investigated whether chronic stress increases plasma norepinephrine and sensitizes colon-specific dorsal root ganglion (DRG) neurons...

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Detalhes bibliográficos
Main Authors: Winston, John H., Xu, Guang-Yin, Sarna, Sushil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813397/
https://ncbi.nlm.nih.gov/pubmed/19800336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.09.054
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