TNF-α antagonists differentially induce TGF-β1-dependent resuscitation of dormant-like Mycobacterium tuberculosis

TNF-α- as well as non-TNF-α-targeting biologics are prescribed to treat a variety of immune-mediated inflammatory disorders. The well-documented risk of tuberculosis progression associated with anti-TNF-α treatment highlighted the central role of TNF-α for the maintenance of protective immunity, alt...

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Vydáno v:PLoS Pathog
Hlavní autoři: Arbués, Ainhoa, Brees, Dominique, Chibout, Salah-Dine, Fox, Todd, Kammüller, Michael, Portevin, Damien
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048311/
https://ncbi.nlm.nih.gov/pubmed/32069329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008312
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