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Inferring TF activation order in time series scRNA-Seq studies

Methods for the analysis of time series single cell expression data (scRNA-Seq) either do not utilize information about transcription factors (TFs) and their targets or only study these as a post-processing step. Using such information can both, improve the accuracy of the reconstructed model and ce...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Lin, Chieh, Ding, Jun, Bar-Joseph, Ziv
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048296/
https://ncbi.nlm.nih.gov/pubmed/32069291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007644
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