Identification of Anti-Mycobacterium and Anti-Legionella Compounds With Potential Distinctive Structural Scaffolds From an HD-PBL Using Phenotypic Screens in Amoebae Host Models

Tubercular Mycobacteria and Legionella pneumophila are the causative agents of potentially fatal respiratory diseases due to their intrinsic pathogenesis but also due to the emergence of antibiotic resistance that limits treatment options. The aim of our study was to explore the antimicrobial activi...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Hanna, Nabil, Kicka, Sébastien, Chiriano, Gianpaolo, Harrison, Christopher, Sakouhi, Hajer Ouertatani, Trofimov, Valentin, Kranjc, Agata, Nitschke, Jahn, Pagni, Marco, Cosson, Pierre, Hilbi, Hubert, Scapozza, Leonardo, Soldati, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047896/
https://ncbi.nlm.nih.gov/pubmed/32153546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00266
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