FGFR1 and FGFR4 oncogenicity depends on n-cadherin and their co-expression may predict FGFR-targeted therapy efficacy

BACKGROUND: Fibroblast growth factor receptor (FGFR)1 and FGFR4 have been associated with tumorigenesis in a variety of tumour types. As a therapeutic approach, their inhibition has been attempted in different types of malignancies, including lung cancer, and was initially focused on FGFR1-amplified...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Quintanal-Villalonga, Álvaro, Ferrer, Irene, Guruceaga, Elizabeth, Cirauqui, Cristina, Marrugal, Ángela, Ojeda, Laura, García, Santiago, Zugazagoitia, Jon, Muñoz-Galván, Sandra, Lopez-Rios, Fernando, Montuenga, Luis, Vicent, Silvestre, Molina-Pinelo, Sonia, Carnero, Amancio, Paz-Ares, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047190/
https://ncbi.nlm.nih.gov/pubmed/32114392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102683
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados