A Truncating Germline Mutation of TINF2 in Individuals with Thyroid Cancer or Melanoma Results in Longer Telomeres

Background: Our genome sequencing analysis revealed a frameshift mutation in the shelterin gene TINF2 in a large family with individuals affected with papillary thyroid carcinoma (PTC) and melanoma. Here, we further characterized the mutation and screened for coding variants in the 6 shelterin genes...

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Detalles Bibliográficos
Publicado en:Thyroid
Main Authors: He, Huiling, Li, Wei, Comiskey, Daniel F., Liyanarachchi, Sandya, Nieminen, Taina T., Wang, Yanqiang, DeLap, Katherine E., Brock, Pamela, de la Chapelle, Albert
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc., publishers 2020
Assuntos:
Thyroid Cancer and Nodules
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047085/
https://ncbi.nlm.nih.gov/pubmed/31928178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2019.0156
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