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CFTR Modulators: The Changing Face of Cystic Fibrosis in the Era of Precision Medicine
Cystic fibrosis (CF) is a lethal inherited disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene, which result in impairment of CFTR mRNA and protein expression, function, stability or a combination of these. Although CF leads to multifaceted clinical manifestations,...
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| Publicado no: | Front Pharmacol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7046560/ https://ncbi.nlm.nih.gov/pubmed/32153386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01662 |
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