Neuronal Glutamatergic Synaptic Clefts Alkalinize Rather Than Acidify during Neurotransmission

The dogma that the synaptic cleft acidifies during neurotransmission is based on the corelease of neurotransmitters and protons from synaptic vesicles, and is supported by direct data from sensory ribbon-type synapses. However, it is unclear whether acidification occurs at non–ribbon-type synapses....

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Stawarski, Michal, Hernandez, Roberto X., Feghhi, Touhid, Borycz, Jolanta A., Lu, Zhiyuan, Agarwal, Andrea B., Reihl, Kelly D., Tavora, Rubens, Lau, A.W.C., Meinertzhagen, Ian A., Renden, Robert, Macleod, Gregory T.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2020
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046337/
https://ncbi.nlm.nih.gov/pubmed/31964719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1774-19.2020
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