Neuronal Glutamatergic Synaptic Clefts Alkalinize Rather Than Acidify during Neurotransmission

The dogma that the synaptic cleft acidifies during neurotransmission is based on the corelease of neurotransmitters and protons from synaptic vesicles, and is supported by direct data from sensory ribbon-type synapses. However, it is unclear whether acidification occurs at non–ribbon-type synapses....

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Udgivet i:J Neurosci
Main Authors: Stawarski, Michal, Hernandez, Roberto X., Feghhi, Touhid, Borycz, Jolanta A., Lu, Zhiyuan, Agarwal, Andrea B., Reihl, Kelly D., Tavora, Rubens, Lau, A.W.C., Meinertzhagen, Ian A., Renden, Robert, Macleod, Gregory T.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046337/
https://ncbi.nlm.nih.gov/pubmed/31964719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1774-19.2020
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