Nonionotropic Action of Endothelial NMDA Receptors on Blood–Brain Barrier Permeability via Rho/ROCK-Mediated Phosphorylation of Myosin

Increase in blood–brain barrier (BBB) permeability is a crucial step in neuroinflammatory processes. We previously showed that N Methyl D Aspartate Receptor (NMDARs), expressed on cerebral endothelial cells forming the BBB, regulate immune cell infiltration across this barrier in the mouse. Here, we...

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Pubblicato in:J Neurosci
Autori principali: Mehra, Anupriya, Guérit, Sylvaine, Macrez, Richard, Gosselet, Fabien, Sevin, Emmanuel, Lebas, Héloïse, Maubert, Eric, De Vries, Helga E., Bardou, Isabelle, Vivien, Denis, Docagne, Fabian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046331/
https://ncbi.nlm.nih.gov/pubmed/31953371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0969-19.2019
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