A mevalonate bypass system facilitates elucidation of plastid biology in malaria parasites

Malaria parasites rely on a plastid organelle for survival during the blood stages of infection. However, the entire organelle is dispensable as long as the isoprenoid precursor, isopentenyl pyrophosphate (IPP), is supplemented in the culture medium. We engineered parasites to produce isoprenoid pre...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Swift, Russell P., Rajaram, Krithika, Liu, Hans B., Dziedzic, Amanda, Jedlicka, Anne E., Roberts, Aleah D., Matthews, Krista A., Jhun, Hugo, Bumpus, Namandje N., Tewari, Shivendra G., Wallqvist, Anders, Prigge, Sean T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046295/
https://ncbi.nlm.nih.gov/pubmed/32059044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008316
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