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Advances in the development of chimeric antigen receptor-T-cell therapy in B-cell acute lymphoblastic leukemia
CD19-targeted chimeric antigen receptor T-cell (CAR-T) therapy is effective in refractory/relapsed (R/R) B-cell acute lymphoblastic leukemia (B-ALL). This review focuses on achievements, current obstacles, and future directions in CAR-T research. A high complete remission rate of 68% to 93% could be...
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| Pubblicato in: | Chin Med J (Engl) |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wolters Kluwer Health
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7046249/ https://ncbi.nlm.nih.gov/pubmed/31977556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CM9.0000000000000638 |
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