Influence of patient characteristics on chimeric antigen receptor T cell therapy in B-cell acute lymphoblastic leukemia

CD19-specific chimeric antigen receptor T cell (CD19 CAR T) therapy has shown high remission rates in patients with refractory/relapsed B-cell acute lymphoblastic leukemia (r/r B-ALL). However, the long-term outcome and the factors that influence the efficacy need further exploration. Here we report...

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Veröffentlicht in:Nat Commun
Hauptverfasser: An, Furun, Wang, Huiping, Liu, Zhenyun, Wu, Fan, Zhang, Jiakui, Tao, Qianshan, Li, Yingwei, Shen, Yuanyuan, Ruan, Yanjie, Zhang, Qing, Pan, Ying, Zhu, Weiwei, Qin, Hui, Wang, Yansheng, Fu, Yongling, Feng, Zhenqing, Zhai, Zhimin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683530/
https://ncbi.nlm.nih.gov/pubmed/33230103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19774-x
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