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Dkk1: A key molecule in joint remodelling and fibrosis

Dickkopf-1 (Dkk-1) is a Wnt signaling pathway inhibitor that has been shown to play an important role in joint remodeling, in experimental models of arthritis and in humans. Recent data suggest that this molecule is involved in the fibrotic process as well. OBJECTIVES: This review summarizes all the...

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Détails bibliographiques
Publié dans:Mediterr J Rheumatol
Auteurs principaux: Klavdianou, Kalliopi, Liossis, Stamatis-Nick, Daoussis, Dimitrios
Format: Artigo
Langue:Inglês
Publié: The Mediterranean Journal of Rheumatology (MJR) 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045998/
https://ncbi.nlm.nih.gov/pubmed/32185280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31138/mjr.28.4.174
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