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Fructo-oligosaccharides ameliorate steatohepatitis, visceral adiposity, and associated chronic inflammation via increased production of short-chain fatty acids in a mouse model of non-alcoholic steatohepatitis

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome. Within the spectrum of NAFLD, non-alcoholic steatohepatitis (NASH) in combination with hepatic inflammation and fibrosis can lead to liver cirrhosis and hepatocellular carcinoma. Dysbiosis was rep...

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Bibliographic Details
Published in:BMC Gastroenterol
Main Authors: Takai, Atsuko, Kikuchi, Kentaro, Ichimura, Mayuko, Tsuneyama, Koichi, Moritoki, Yuki, Matsumoto, Kotaro, Tsunashima, Hiromichi, Onda, Takeshi, Kuniyoshi, Noriyuki, Nariyama, Tomoyuki, Ohyatsu, Sho, Kubota, Juri, Nagumo, Kozue, Sato, Shinpei, Hara, Masumi, Miyakawa, Hiroshi
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045471/
https://ncbi.nlm.nih.gov/pubmed/32103741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-020-01194-2
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