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C9ORF72-ALS/FTD: Transgenic Mice Make a Come-BAC
For five years, since the landmark discovery of the C9ORF72 hexanucleotide repeat expansion in ALS/FTD, a transgenic mouse model has remained elusive. Now, two laboratories (Liu et al., 2016; Jiang et al., 2016) report the development of BAC transgenic mice that recapitulate features of the human di...
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| Publicado no: | Neuron |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7045171/ https://ncbi.nlm.nih.gov/pubmed/27151634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.04.026 |
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