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FMR1 CGG allele length in Israeli BRCA1/BRCA2 mutation carriers and the general population display distinct distribution patterns

Premature ovarian failure and diminished ovarian reserve have been noted both in female BRCA1/BRCA2 mutation carriers and in carriers of the Fragile X syndrome FMR1 gene CGG repeat size premutation. Based on the observation that BRCA mutation carriers do not harbour long CGG repeats in the FMR1 gene...

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Detalhes bibliográficos
Publicado no:Genet Res (Camb)
Main Authors: LAITMAN, YAEL, RIES-LEVAVI, LIAT, BERKENSDADT, MICHAL, KORACH, JACOB, PERRI, TAMAR, PRAS, ELON, FRIEDMAN, EITAN
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045097/
https://ncbi.nlm.nih.gov/pubmed/25579682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0016672314000147
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