Phenotypic characteristics of colorectal cancer in BRCA1/2 mutation carriers

Mutations in the BRCA1/2 genes were recently shown to be associated with an increased risk for colorectal cancer. We characterized the largest cohort available of BRCA1/2 mutation carriers with colorectal cancer. We analyzed 32 patients with lower gastrointestinal cancers and germline BRCA1/2 mutati...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Grinshpun, Albert, Halpern, Naama, Granit, Roy Zvi, Hubert, Ayala, Hamburger, Tamar, Laitman, Yael, Shacham-Shmueli, Einat, Peerless, Yehudit, Friedman, Eitan, Peretz, Tamar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839043/
https://ncbi.nlm.nih.gov/pubmed/29321669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-017-0067-1
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