Phosphoprotein Gene of Wild-Type Rabies Virus Plays a Role in Limiting Viral Pathogenicity and Lowering the Enhancement of BBB Permeability

Enhancement of blood–brain barrier (BBB) permeability is necessary for clearing virus in the central nervous system (CNS). It has been reported that only laboratory-attenuated rabies virus (RABV) induces inflammatory response to lead BBB transient breakdown rather than wild-type (wt) strains. As a c...

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Udgivet i:Front Microbiol
Main Authors: Long, Teng, Zhang, Boyue, Fan, Ruqi, Wu, Yuting, Mo, Meijun, Luo, Jun, Chang, Yiran, Tian, Qin, Mei, Mingzhu, Jiang, He, Luo, Yongwen, Guo, Xiaofeng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045047/
https://ncbi.nlm.nih.gov/pubmed/32153520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00109
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