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Phosphoprotein Gene of Wild-Type Rabies Virus Plays a Role in Limiting Viral Pathogenicity and Lowering the Enhancement of BBB Permeability

Enhancement of blood–brain barrier (BBB) permeability is necessary for clearing virus in the central nervous system (CNS). It has been reported that only laboratory-attenuated rabies virus (RABV) induces inflammatory response to lead BBB transient breakdown rather than wild-type (wt) strains. As a c...

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Bibliografske podrobnosti
izdano v:Front Microbiol
Main Authors: Long, Teng, Zhang, Boyue, Fan, Ruqi, Wu, Yuting, Mo, Meijun, Luo, Jun, Chang, Yiran, Tian, Qin, Mei, Mingzhu, Jiang, He, Luo, Yongwen, Guo, Xiaofeng
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045047/
https://ncbi.nlm.nih.gov/pubmed/32153520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00109
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