Phosphoprotein Gene of Wild-Type Rabies Virus Plays a Role in Limiting Viral Pathogenicity and Lowering the Enhancement of BBB Permeability

Enhancement of blood–brain barrier (BBB) permeability is necessary for clearing virus in the central nervous system (CNS). It has been reported that only laboratory-attenuated rabies virus (RABV) induces inflammatory response to lead BBB transient breakdown rather than wild-type (wt) strains. As a c...

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Dettagli Bibliografici
Pubblicato in:Front Microbiol
Autori principali: Long, Teng, Zhang, Boyue, Fan, Ruqi, Wu, Yuting, Mo, Meijun, Luo, Jun, Chang, Yiran, Tian, Qin, Mei, Mingzhu, Jiang, He, Luo, Yongwen, Guo, Xiaofeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045047/
https://ncbi.nlm.nih.gov/pubmed/32153520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00109
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