Phosphoprotein Gene of Wild-Type Rabies Virus Plays a Role in Limiting Viral Pathogenicity and Lowering the Enhancement of BBB Permeability

Enhancement of blood–brain barrier (BBB) permeability is necessary for clearing virus in the central nervous system (CNS). It has been reported that only laboratory-attenuated rabies virus (RABV) induces inflammatory response to lead BBB transient breakdown rather than wild-type (wt) strains. As a c...

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Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Long, Teng, Zhang, Boyue, Fan, Ruqi, Wu, Yuting, Mo, Meijun, Luo, Jun, Chang, Yiran, Tian, Qin, Mei, Mingzhu, Jiang, He, Luo, Yongwen, Guo, Xiaofeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045047/
https://ncbi.nlm.nih.gov/pubmed/32153520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00109
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