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Genotyping and Copy Number Analysis of Immunoglobin Heavy Chain Variable Genes Using Long Reads

One of the remaining challenges to describing an individual's genetic variation lies in the highly heterogeneous and complex genomic regions that impede the use of classical reference-guided mapping and assembly approaches. Once such region is the Immunoglobulin heavy chain locus (IGH), which i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:iScience
Egile Nagusiak: Ford, Michael, Haghshenas, Ehsan, Watson, Corey T., Sahinalp, S. Cenk
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044747/
https://ncbi.nlm.nih.gov/pubmed/32109676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100883
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