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Estimating Copy Number and Allelic Variation at the Immunoglobulin Heavy Chain Locus Using Short Reads

The study of genomic regions that contain gene copies and structural variation is a major challenge in modern genomics. Unlike variation involving single nucleotide changes, data on the variation of copy number is difficult to collect and few tools exist for analyzing the variation between individua...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Luo, Shishi, Yu, Jane A., Song, Yun S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025152/
https://ncbi.nlm.nih.gov/pubmed/27632220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005117
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