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CREB Family Transcription Factors Are Major Mediators of BDNF Transcriptional Autoregulation in Cortical Neurons

BDNF signaling via its transmembrane receptor TrkB has an important role in neuronal survival, differentiation, and synaptic plasticity. Remarkably, BDNF is capable of modulating its own expression levels in neurons, forming a transcriptional positive feedback loop. In the current study, we have inv...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Esvald, Eli-Eelika, Tuvikene, Jürgen, Sirp, Alex, Patil, Sudarshan, Bramham, Clive R., Timmusk, Tõnis
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044735/
https://ncbi.nlm.nih.gov/pubmed/31915257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0367-19.2019
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