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CREB Family Transcription Factors Are Major Mediators of BDNF Transcriptional Autoregulation in Cortical Neurons

BDNF signaling via its transmembrane receptor TrkB has an important role in neuronal survival, differentiation, and synaptic plasticity. Remarkably, BDNF is capable of modulating its own expression levels in neurons, forming a transcriptional positive feedback loop. In the current study, we have inv...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Esvald, Eli-Eelika, Tuvikene, Jürgen, Sirp, Alex, Patil, Sudarshan, Bramham, Clive R., Timmusk, Tõnis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044735/
https://ncbi.nlm.nih.gov/pubmed/31915257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0367-19.2019
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