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CREB Family Transcription Factors Are Major Mediators of BDNF Transcriptional Autoregulation in Cortical Neurons

BDNF signaling via its transmembrane receptor TrkB has an important role in neuronal survival, differentiation, and synaptic plasticity. Remarkably, BDNF is capable of modulating its own expression levels in neurons, forming a transcriptional positive feedback loop. In the current study, we have inv...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Esvald, Eli-Eelika, Tuvikene, Jürgen, Sirp, Alex, Patil, Sudarshan, Bramham, Clive R., Timmusk, Tõnis
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044735/
https://ncbi.nlm.nih.gov/pubmed/31915257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0367-19.2019
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