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Maternal Experience-Dependent Cortical Plasticity in Mice Is Circuit- and Stimulus-Specific and Requires MECP2

The neurodevelopmental disorder Rett syndrome is caused by mutations in the gene Mecp2. Misexpression of the protein MECP2 is thought to contribute to neuropathology by causing dysregulation of plasticity. Female heterozygous Mecp2 mutants (Mecp2(het)) failed to acquire a learned maternal retrieval...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Lau, Billy Y.B., Krishnan, Keerthi, Huang, Z. Josh, Shea, Stephen D.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044728/
https://ncbi.nlm.nih.gov/pubmed/31911459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1964-19.2019
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