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Maternal Experience-Dependent Cortical Plasticity in Mice Is Circuit- and Stimulus-Specific and Requires MECP2

The neurodevelopmental disorder Rett syndrome is caused by mutations in the gene Mecp2. Misexpression of the protein MECP2 is thought to contribute to neuropathology by causing dysregulation of plasticity. Female heterozygous Mecp2 mutants (Mecp2(het)) failed to acquire a learned maternal retrieval...

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Pubblicato in:J Neurosci
Autori principali: Lau, Billy Y.B., Krishnan, Keerthi, Huang, Z. Josh, Shea, Stephen D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044728/
https://ncbi.nlm.nih.gov/pubmed/31911459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1964-19.2019
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