Significance of p53-Binding Protein 1 Nuclear Foci in Cervical Squamous Intraepithelial Lesions: Association With High-Risk Human Papillomavirus Infection and P16(INK4a) Expression

As p53-binding protein 1 (53BP1) localizes to the sites of DNA double-strand breaks and rapidly forms nuclear foci (NF), and its presence may be an indicator of endogenous genomic instability (GIN). We previously showed that 53BP1 NF in cervical cells increase with neoplastic progression, indicating...

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Vydáno v:Cancer Control
Hlavní autoři: Kawashita, Sayaka, Matsuda, Katsuya, Kondo, Hisayoshi, Kitajima, Yuriko, Hasegawa, Yuri, Shimada, Takako, Kitajima, Michio, Miura, Kiyonori, Nakashima, Masahiro, Masuzaki, Hideaki
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044491/
https://ncbi.nlm.nih.gov/pubmed/32077330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1073274819901170
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