Significance of p53-Binding Protein 1 Nuclear Foci in Cervical Squamous Intraepithelial Lesions: Association With High-Risk Human Papillomavirus Infection and P16(INK4a) Expression

As p53-binding protein 1 (53BP1) localizes to the sites of DNA double-strand breaks and rapidly forms nuclear foci (NF), and its presence may be an indicator of endogenous genomic instability (GIN). We previously showed that 53BP1 NF in cervical cells increase with neoplastic progression, indicating...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancer Control
Main Authors: Kawashita, Sayaka, Matsuda, Katsuya, Kondo, Hisayoshi, Kitajima, Yuriko, Hasegawa, Yuri, Shimada, Takako, Kitajima, Michio, Miura, Kiyonori, Nakashima, Masahiro, Masuzaki, Hideaki
פורמט: Artigo
שפה:Inglês
יצא לאור: SAGE Publications 2020
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044491/
https://ncbi.nlm.nih.gov/pubmed/32077330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1073274819901170
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