Significance of p53-Binding Protein 1 Nuclear Foci in Cervical Squamous Intraepithelial Lesions: Association With High-Risk Human Papillomavirus Infection and P16(INK4a) Expression

As p53-binding protein 1 (53BP1) localizes to the sites of DNA double-strand breaks and rapidly forms nuclear foci (NF), and its presence may be an indicator of endogenous genomic instability (GIN). We previously showed that 53BP1 NF in cervical cells increase with neoplastic progression, indicating...

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Dettagli Bibliografici
Pubblicato in:Cancer Control
Autori principali: Kawashita, Sayaka, Matsuda, Katsuya, Kondo, Hisayoshi, Kitajima, Yuriko, Hasegawa, Yuri, Shimada, Takako, Kitajima, Michio, Miura, Kiyonori, Nakashima, Masahiro, Masuzaki, Hideaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044491/
https://ncbi.nlm.nih.gov/pubmed/32077330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1073274819901170
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