FAM172A inhibits EMT in pancreatic cancer via ERK-MAPK signaling

FAM172A, as a newly discovered gene, is little known in cancer development, especially in pancreatic cancer (PC). We investigated the potential role and molecular mechanism of FAM172A in epithelial to mesenchymal transition (EMT) in both human clinical samples and PC cells. FAM172A was downregulated...

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Bibliografiske detaljer
Udgivet i:Biol Open
Main Authors: Chen, Ying, Liu, Peihui, Shen, Di, Liu, Han, Xu, Lepeng, Wang, Jian, Shen, Daguang, Sun, He, Wu, Hongkui
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044457/
https://ncbi.nlm.nih.gov/pubmed/31988090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.048462
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