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Dinucleoside polyphosphates act as 5′-RNA caps in bacteria
It has been more than 50 years since the discovery of dinucleoside polyphosphates (Np(n)Ns) and yet their roles and mechanisms of action remain unclear. Here, we show that both methylated and non-methylated Np(n)Ns serve as RNA caps in Escherichia coli. Np(n)Ns are excellent substrates for T7 and E....
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| 發表在: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7044304/ https://ncbi.nlm.nih.gov/pubmed/32103016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14896-8 |
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