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Adenosine 5’-monophosphate protects from hypoxia by lowering mitochondrial metabolism and oxygen demand

Ischemia and reperfusion injury following severe trauma or cardiac arrest are major causes of organ damage in intensive care patients. The brain is particularly vulnerable because hypoxia rapidly damages neurons due to their heavy reliance on oxidative phosphorylation. Therapeutic hypothermia can re...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Kondo, Yutaka, Sueyoshi, Koichiro, Zhang, Jingping, Bao, Yi, Li, Xiaoou, Fakhari, Mahtab, Slubowski, Christian J., Bahrami, Soheyl, Ledderose, Carola, Junger, Wolfgang G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044067/
https://ncbi.nlm.nih.gov/pubmed/31460871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001440
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