Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2

Malaria parasites suppress host immune responses to facilitate their survival, but the underlying mechanism remains elusive. Here, we found that blood-stage malaria parasites predominantly induced CD4(+)Foxp3(+)CD25(+) regulatory T cells to release soluble fibrinogen-like protein 2 (sFGL2), which su...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Fu, Yong, Ding, Yan, Wang, Qinghui, Zhu, Feng, Tan, Yulong, Lu, Xiao, Guo, Bo, Zhang, Qingfeng, Cao, Yaming, Liu, Taiping, Cui, Liwang, Xu, Wenyue
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043914/
https://ncbi.nlm.nih.gov/pubmed/32133407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay9269
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