Ameliorative effects of silymarin on HCl-induced acute lung injury in rats; role of the Nrf-2/HO-1 pathway

OBJECTIVE(S): Aspiration is a common cause of acute lung injury (ALI), which lacks an effective treatment. Inflammation and oxidative stress play key roles in ALI development. Silymarin is an active extract of Silybum marianum plant seeds (milk thistle). Silymarin has potent anti-inflammatory and an...

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Vydáno v:Iran J Basic Med Sci
Hlavní autoři: Ahmed, Rasha F, Moussa, Rabab A, Eldemerdash, Reda S, Zakaria, Mahmoud M, Abdel-Gaber, Seham A
Médium: Artigo
Jazyk:Inglês
Vydáno: Mashhad University of Medical Sciences 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043873/
https://ncbi.nlm.nih.gov/pubmed/32133068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2019.14069
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