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Radical α-C–H Cyclobutylation of Aniline Derivatives

A catalytic system has been developed for the direct alkylation of α-C–H bonds of aniline derivatives with strained C–C σ-bonds. This method operates through a photoredox mechanism in which oxidative formation of aminoalkyl radical intermediates enables addition to a bicyclobutane derivative, giving...

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Bibliographic Details
Published in:Synlett
Main Authors: Pratt, Cameron J., Aycock, R. Adam, King, Max D., Jui, Nathan T.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043791/
https://ncbi.nlm.nih.gov/pubmed/32103861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0039-1690197
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