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Synthesis of Spirocyclic Piperidines by Radical Hydroarylation

Reported here are conditions for the construction of spirocyclic piperidines from linear aryl halide precursors. These conditions employ a strongly reducing organic photoredox catalyst in combination with a trialkylamine reductant to achieve formation of aryl radical species. Regioselective cyclizat...

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Bibliografiske detaljer
Udgivet i:Synlett
Main Authors: Spurlin, Racheal M., Harris, Amber L., Pratt, Cameron J., Jui, Nathan T.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318207/
https://ncbi.nlm.nih.gov/pubmed/34326573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/a-1315-1014
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