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Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions

Temozolomide (TMZ) is a drug of choice in glioblastoma treatment. Its therapeutic applications expand also beyond high grade gliomas. However, a significant number of recurrences and resistance to the drug is observed. The key factor in each chemotherapy is to achieve the therapeutic doses of a drug...

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Pubblicato in:PLoS One
Autori principali: Belter, Agnieszka, Barciszewski, Jakub, Barciszewska, Anna-Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043761/
https://ncbi.nlm.nih.gov/pubmed/32101575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229534
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