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A260 THE LACK OF CHROMOGRANIN-A MODIFIES THE GUT MICROBIOTA COMPOSITION AND REGULATES EXPERIMENTAL COLONIC INFLAMMATION

BACKGROUND: Ulcerative colitis (UC)is characterized by distinct changes in the gut microbiome and elevated chromogranin-A (CHGA) level, which seem to be a relevant pathogenetic mechanism.CHGA, a prohormone produced by enterochromaffin (EC) cells and cleaved into several bioactive peptides, regulates...

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Publicat a:J Can Assoc Gastroenterol
Autors principals: Eissa, N, Diarra, A, Hussein, H, Bernstein, C N, Ghia, J
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043596/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz047.259
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