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A212 CHROMOFUNGIN PROTECTS AGAINST DSS-INDUCED COLITIS BY REGULATING P-53 APOPTITIC PATHWAY

BACKGROUND: Development of ulcerative colitis is associated with epithelial apoptosis mediated by p53-apoptotic pathway through the activation B-cell lymphoma 2 (Bcl-2), Bcl-2 associated-X protein (BAX) and Bcl-2 antagonist/killer-1 (BAK1) proteins. Chromofungin (CHR), a chromogranin-A derived pepti...

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Bibliografiske detaljer
Udgivet i:J Can Assoc Gastroenterol
Main Authors: Diarra, A, Eissa, N, Ghia, J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043703/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz047.211
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