A19 NOVEL HLA-DQ2 TRANSGENIC MICE DEVELOP GLUTEN-IMMUNOPATHOLOGY FOLLOWING GLUTEN SENSITIZATION

BACKGROUND: Celiac disease (CeD), an autoimmune and chronic inflammatory enteropathy triggered by the ingestion of gluten, is associated with HLA-DQ2 (~90%) and, to a lesser extent, HLA-DQ8. We previously characterized a humanized mouse model of gluten sensitivity that expresses the HLA-DQ8 allele,...

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Bibliografiske detaljer
Udgivet i:J Can Assoc Gastroenterol
Main Authors: Clarizio, A V, Galipeau, H J, Jury, J, Rondeau, L, Godbout, J, Williams, L, Anderson, B, Verdu, E
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Oral Presentations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043420/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz047.018
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