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Inhibition of the inflammasome signaling cascade reduces alcohol consumption in female but not male mice

BACKGROUND: Alcohol use disorder is a significant societal and medical burden that is associated with both organ pathology and addiction. Excessive alcohol use results in neuroinflammation characterized by activation of the inflammasome, a multiprotein complex, and IL-1β increase in the brain. Recen...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Lowe, Patrick P., Cho, Yeonhee, Tornai, David, Coban, Sahin, Catalano, Donna, Szabo, Gyongyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043385/
https://ncbi.nlm.nih.gov/pubmed/31854009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14272
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