IκB kinase 2 is not essential for platelet activation

Platelets are small anucleate cells that release a plethora of molecules to ensure functional hemostasis. It has been reported that IκB kinase 2 (IKK2), the central enzyme of the inflammatory NF-κB pathway, is involved in platelet activation, because megakaryocyte/platelet-specific deletion of exons...

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Bibliographic Details
Published in:Blood Adv
Main Authors: Salzmann, Manuel, Bleichert, Sonja, Moser, Bernhard, Mussbacher, Marion, Haase, Mildred, Hoesel, Bastian, Schrottmaier, Waltraud C., Kral-Pointner, Julia B., Itakura, Makoto, Schmidt, Katy, Assinger, Alice, Schmid, Johannes A.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2020
Subjects:
Platelets and Thrombopoiesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042989/
https://ncbi.nlm.nih.gov/pubmed/32074278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001044
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