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A Robust Method Uncovers Significant Context-Specific Heritability in Diverse Complex Traits
Gene-environment interactions (GxE) can be fundamental in applications ranging from functional genomics to precision medicine and is a conjectured source of substantial heritability. However, unbiased methods to profile GxE genome-wide are nascent and, as we show, cannot accommodate general environm...
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| Publicado no: | Am J Hum Genet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7042488/ https://ncbi.nlm.nih.gov/pubmed/31901249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.11.015 |
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