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Percutaneous absorption and brain distribution facilitation of borneol on tetramethylpyrazine in a microemulsion-based transdermal therapeutic system

In this study, we show that the percutaneous absorption and brain distribution of tetramethylpyrazine (TMP) is enhanced when combined with borneol (BN) in a microemulsion-based transdermal therapeutic system (ME-TTS). The formulation of the TMP and BN microemulsion (TEM-BN-ME) was optimized in skin...

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Detalhes bibliográficos
Publicado no:Asian J Pharm Sci
Main Authors: Hu, Xiaoge, Cheng, Ning, Zhao, Jihui, Piao, Xianghua, Yan, Yulu, Zhang, Qibo, Zhou, Kuan, Zhang, Yongtai, Feng, Nianping
Formato: Artigo
Idioma:Inglês
Publicado em: Shenyang Pharmaceutical University 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042483/
https://ncbi.nlm.nih.gov/pubmed/32104460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2018.06.003
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