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Microemulsion-based novel transdermal delivery system of tetramethylpyrazine: preparation and evaluation in vitro and in vivo
OBJECTIVE: To deliver 2,3,5,6-tetramethylpyrazine (TMP) in a relatively large dose through a transdermal route and facilitate the practical application of microemulison in transdermal drug delivery. METHODS: The pseudo-ternary phase diagram for microemulsion regions was constructed using isopropyl m...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Dove Medical Press
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160947/ https://ncbi.nlm.nih.gov/pubmed/21904451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S23597 |
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