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DNA damage and expression of DNA methylation modulators in urine-derived cells of patients with hypertension and diabetes

Diabetes and hypertension have become the primary causes of chronic kidney disease worldwide. However, there are no established markers for early diagnosis or predicting renal prognosis. Here, we investigated the expression profiles of DNA repair and DNA methylation factors in human urine-derived ce...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Hishikawa, Akihito, Hayashi, Kaori, Yoshimoto, Norifumi, Nakamichi, Ran, Homma, Koichiro, Itoh, Hiroshi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042287/
https://ncbi.nlm.nih.gov/pubmed/32099032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60420-9
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