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Association of glomerular DNA damage and DNA methylation with one-year eGFR decline in IgA nephropathy
Accumulation of DNA double-strand breaks (DSBs) is linked to aging and age-related diseases. We recently reported the possible association of DNA DSBs with altered DNA methylation in murine models of kidney disease. However, DSBs and DNA methylation in human kidneys was not adequately investigated....
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6959244/ https://ncbi.nlm.nih.gov/pubmed/31937846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57140-0 |
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