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FK506 regulates Ca(2+) release evoked by inositol 1,4,5‐trisphosphate independently of FK‐binding protein in endothelial cells
BACKGROUND AND PURPOSE: FK506 and rapamycin are modulators of FK‐binding proteins (FKBP) that are used to suppress immune function after organ and hematopoietic stem cell transplantations. The drugs share the unwanted side‐effect of evoking hypertension that is associated with reduced endothelial fu...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7042112/ https://ncbi.nlm.nih.gov/pubmed/31705533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14905 |
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